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Abnova/c-Myc tag recombinant monoclonal antibody, clone 9E10/1kit/RAB00199
  • Abnova/c-Myc tag recombinant monoclonal antibody, clone 9E10/1kit/RAB00199

Abnova/c-Myc tag recombinant monoclonal antibody, clone 9E10/1kit/RAB00199

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貨號(hào): RAB00199
品牌: Abnova
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  • 詳情
  • 使用說(shuō)明
  • 常見(jiàn)問(wèn)題
      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Recombinant human monoclonal antibody raised against c-Myc tag.
      • Immunogen:
      • Original antibody is raised against a synthetic peptide corresponding to amino acids 408-439 at C-terminus of human c-Myc.
      • Reactivity:
      • Human
      • Specificity:
      • Epitope sequence is amino acids 410-419 of human c-myc protein (EQKLISEEDL).
      • Form:
      • Liquid
      • Purification:
      • Protein A affinity purification
      • Isotype:
      • IgG3, kappa
      • Recommend Usage:
      • ImmunofluorescenceImmunohistochemistryImmunoprecipitationWestern BlotThe optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (0.02% Proclin 300).
      • Storage Instruction:
      • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Antibody Species:
      • Human
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot
      • Immunohistochemistry
      • Immunofluorescence
      • Immunoprecipitation
      • Application Image
      • Western Blot
      • Immunohistochemistry
      • Immunofluorescence
      • Immunoprecipitation
      • Gene Information
      • Entrez GeneID:
      • 4609
      • Gene Name:
      • MYC
      • Gene Alias:
      • bHLHe39,c-Myc
      • Gene Description:
      • v-myc myelocytomatosis viral oncogene homolog (avian)
      • Omim ID:
      • 113970, 190080
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt"s lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
      • Other Designations:
      • avian myelocytomatosis viral oncogene homolog,myc proto-oncogene protein,v-myc avian myelocytomatosis viral oncogene homolog
      • Gene Pathway
      • Acute myeloid leukemia
      • Bladder cancer
      • Cell cycle
      • Chronic myeloid leukemia
      • Colorectal cancer
      • Endometrial cancer
      • ErbB signaling pathway
      • Jak-STAT signaling pathway
      • MAPK signaling pathway
      • Pathways in cancer
      • Small cell lung cancer
      • TGF-beta signaling pathway
      • Thyroid cancer
      • Wnt signaling pathway
      • Related Disease
      • Alzheimer Disease
      • Alzheimer disease
      • Breast cancer
      • Breast Neoplasms
      • Carcinoma, Non-Small-Cell Lung
      • Carcinoma, Squamous Cell
      • Cardiovascular Diseases
      • Chromosome Aberrations
      • Colorectal Neoplasms
      • Diabetes Complications
      • Disease Progression
      • Genetic Predisposition to Disease
      • Helicobacter Infections
      • Hematologic Diseases
      • Hodgkin Disease
      • Kidney Failure, Chronic
      • Lung Neoplasms
      • Lymphoma, B-Cell
      • Lymphoma, B-Cell, Marginal Zone
          • ... see more
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