The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
53BP1 (Phospho-Ser6) Antibody
Synonyms
p53-binding protein 1; P531; TP53B; TP53BP1; TRP53BP1; Tumor suppressor p53-binding protein 1
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human 53BP1 around the phosphorylation site of Ser6.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
Specificity
53BP1 (Phospho-Ser6) Antibody detects endogenous levels of TP53BP1 only when phosphorylated at Ser6.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
TP53BP1
Database Links
Gene ID: 7158 Swiss-Prot #: Q12888
OMIM #: 605230 Unigene #: Hs.440968
Target Modification
Phospho
Modification Sites
H:S6, M:S6, R:S11
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using 53BP1 (Phospho-Ser6) Antibody
Image 2
Western blot analysis of lysates from COS7 cells treated with insulin 0.01U/ML 15', using 53BP1 (Phospho-Ser6) Antibody.