Description: | Form Uniform Spheroids with Ultra-Low Attachment PrimeSurface? Cell Culture Plates: PrimeSurface? culture ware are ultra-low attachment (ULA) dishes and plates that promote scaffold free, self-assembly of spheroid formation. The plates are pre-coated with unique ultra-hydrophilic polymer that enables spontaneous spheroid formation of uniform size and shape. The ULA plates have high optical clarity making them highly suitable for bright field imaging and confocal microscopy.In addition to the widely used 96 well U bottom plate, 96 well plates are also available in V and M bottom, giving scientists a choice to form tighter spheroids that are needed for specific cell types.For high throughput screening (HTS) needs, 384 well plates are available in clear and white. 384 white plates are suitable for chemiluminescence assays screening. Chemiluminescent assays often outperform analogous fluorescent assays due to its’ low background offering a high signal to noise ratio, thus providing higher assay sensitivity. Spheroid tumor cells are typically generated using ULA plates and other 3D cell culturing methods, however transferring them without damaging the spheroids to a 2D white plate for luminescent assay screening can be challenging.Using PrimeSurface? 96 and 384 well ULA white plates, cancer spheroid cells can be formed and analyzed in the same multi-well plate for luminescence assays. S-BIO’s 3D Cell Culture products are used for stem cell research, drug discovery & development, tissue engineering & regenerative medicine. |