Properties:
RelatedCategories | BloodandUrineChemistryAssayKits,CellBIOLOGy,EnzymaticActivityAssayKits,EnzymaticKitsfortheQuantitationofNutrientsandMetabolites,MetabolismAssayKitsA-Z, |
storagetemp. | −20°C |
Description:
Generaldescription
AdenylateKinase(AK)(EC2.7.4.3)isanabundantenzymeinvolvedinenergymetabolismandhomeostasisofcellularadeninenucleotideratiosindifferentintracellularcompartments.Theenzymeisfoundinthenucleus,cytosol,ormitochondria(intermembranespaceormatrix)ofvariouskindsoftissues.AdenylatekinaseactsontwomoleculesofADPtogenerateATPandAMP.Nineisoformsofadenylatekinasehavebeenidentified.Erythrocyteadenylatekinasedeficiencyisassociatedwithhemolyticanemia.Adenylatekinasealsoplaysanimportantroleinpost-ischemicrecoveryandinapoptosis.
SuitABIlity
SuitableforthedetectionofAdenylateKinaseincell/tissuehomogenate,mitochondriallysate,orpurifiedprotein.