當(dāng)前位置 : Millipore >>> Millipore/MAB1621 | Anti-Neurofilament 145 kDa Antibody, CT, clone 3H11/MAB1621/300 µL
Millipore/MAB1621 | Anti-Neurofilament 145 kDa Antibody, CT, clone 3H11/MAB1621/300 µL
  • Millipore/MAB1621 | Anti-Neurofilament 145 kDa Antibody, CT, clone 3H11/MAB1621/300 µL

Millipore/MAB1621 | Anti-Neurofilament 145 kDa Antibody, CT, clone 3H11/MAB1621/300 µL

價格: ¥3072.00 市場價: 5120.00

貨號: MAB1621
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品:無質(zhì)量問題不接受退換貨,下單前請仔細(xì)核對信息。
下單后請及時聯(lián)系客服核對商品價格,訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費服務(wù)熱線

4000-520-616


  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberMAB1621
      BrandFamilyChemicon®
      TradeName
      • Chemicon
      DescriptionAnti-Neurofilament145kDaAntibody,CT,clone3H11
      BackgroundInformationNeurofilamentsareatypeofintermediatefilamentthatserveasmajorelementsoftheCytoskeletonsupportingtheaxoncytoplasm.Theyarethemostabundantfibrillarcomponentsoftheaxon,beingonaverage3-10timesmorefrequentthanaxonalmicrotubules.Neurofilaments(10nmindia.)arebuiltfromthreeintertwinedprotofibrilswhicharethemselvescomposedoftwotetramericprotofilamentcomplexsofmonomericproteins.Theneurofilamenttripletproteins(68/70,160,and200kDa)occurinboththecentralandperipheralnervoussystemandareusuallyneuronspecific.The68/70kDaNF-Lproteincanself-assembleintoafilamentousstructure,howeverthe160kDaNF-Mand200kDaNF-Hproteinsrequirethepresenceofthe68/70kDaNF-Lproteintoco-assemble.Neuromas,ganglioneuromas,gangliogliomas,ganglioneuroblastomasandneuroblastomasstainpositivelyforneurofilaments.Althoughtypicallyrestrictedtoneurons,neurofilamentshavebeendetectedinparagangliomasandadrenalandextra-adrenalpheochromocytomas.Carcinoids,neuroendocrinecarcinomasoftheskin,andoatcellcarcinomasofthelungalsoexpressneurofilaments.FormoreneurofilamentinformationseeNervousSystemCellTypeSpecificMarkerchartonlineundertheCHEMICONTechnicalSupportsection.
      ProductInformation
      FormatCultureSupernatant
      StorageandShippingInformation
      StorageConditionsMaintainat-20°Cinundilutedaliquotsforupto12months.Avoidrepeatedfreeze/thawcycles.
      Applications
      ApplicationAnti-Neurofilament145kDaAntibody,C-terminus,clone3H11detectslevelofNeurofilament145kDa&hasbeenpublished&validatedforuseinWB,IC,IH.
      KeyApplications
      • WesternBlotting
      • Immunocytochemistry
      • Immunohistochemistry
      ApplicationNotesImmunohistochemistry:1:50-1:1000;freshfrozen,4%PFAfixedtissuesections

      Immunoblotting:1:1000-1:2000ECLdetection.

      Optimalworkingdilutionsmustbedeterminedbyenduser.
      BIOLOGicalInformation
      ImmunogenRecombinantfusionproteincontainingthelast168aminoacidsofratNF-M.PurifiedfromE.ColiinclusionbodiesbyionexchangechromatographyonDEAE-cellulosein6Murea.
      EpitopeC-terminus
      Clone3H11
      HostMouse
      SpecificityReactswithanepitopedependentonthelast84aminoacidsofratNF-M(145K).ReactsspecificallywithNF-Mfromavarietyofmammalianandavianspecies.Theantibodyisnotsensitivetothephosphorylationstateoftheneurofilament.
      IsotypeIgG1
      SpeciesReactivity
      • Avian
      • Mammals
      AntibodyTypeMonoclonalAntibody
      EntrezGeneNumber
      GeneSymbol
      • NEFM
      • NF-M
      • NEF3
      • NFM
      UniProtNumber
      UniProtSummaryFUNCTION:SwissProt:P07197#Neurofilamentsusuallycontainthreeintermediatefilamentproteins:L,M,andHwhichareinvolvedinthemaintenanceofneuronalcaliber.
      SIZE:916aminoacids;102448Da
      PTM:ThereareanumberofrepeatsofthetripeptideK-S-P,NFMisphosphorylatedonanumberoftheserinesinthismotif.ItisthoughtthatphosphorylationofNFMresultsintheformationofinterfilamentcrossbridgesthatareimportantinthemaintenanceofaxonalcaliber.&Phosphorylationseemstoplayamajorroleinthefunctioningofthelargerneurofilamentpolypeptides(NF-MandNF-H),thelevelsofphosphorylationbeingaltereddevelopmentallyandcoincidentwithachangeintheneurofilamentfunction.
      SIMILARITY:SwissProt:P07197##Belongstotheintermediatefilamentfamily.
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188,秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度,由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后,保障正品優(yōu)質(zhì)。以“快速好省,為科研提供好產(chǎn)品、好價格”為理念,直接鏈接原廠家,從全國各地原制造商嚴(yán)格挑選188款科研精品,剔除品牌溢價,188生物新電商,把好的產(chǎn)品帶給科研!? 力求給你最優(yōu)質(zhì)的商品。
  • Q:生物188產(chǎn)品正品保障嗎?
    A:生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗,在業(yè)界享有良好的口碑;自營商城,直接從廠家采購, 自己的團隊負(fù)責(zé)國際物流和清關(guān),中間沒有第三方,所有流程嚴(yán)格把控,100%保證正品,假一罰十。

    Q:下單后可以修改訂單嗎?
    A:下單后的商品付款之前可以修改;訂單付款成功,需要聯(lián)系我們客服進行修改;客服電話:4000-520-616

    Q:可以開發(fā)票嗎?
    A:本網(wǎng)站所售商品都是正規(guī)清關(guān),均開具16%正規(guī)發(fā)票,發(fā)票金額含配送費金額,另有說明的除外。

    Q:商品幾天可以發(fā)貨?
    A:生物188商品,全部現(xiàn)貨銷售,付款后即可發(fā)貨,一般一周內(nèi)送達!

    Q:如何聯(lián)系商家?
    A:有任何問題夠可以電話咨詢我們,全國24小時免費服務(wù)熱線:4000-520-616 或聯(lián)系我們的在線客服QQ:1570468124

    Q:收到的商品少了/發(fā)錯了怎么辦?
    A:同個訂單購買多個商品可能會分為一個以上包裹發(fā)出,可能不會同時送達,建議查看訂單詳情是否是 部分發(fā)貨狀態(tài);如未收到,可聯(lián)系在線客服或者致電4000-520-616。

    Q:退換貨/維修需要多長時間?
    A:一般情況下,退貨處理周期為客戶收到產(chǎn)品一個月內(nèi)(以快遞公司顯示簽收時間為準(zhǔn)),包裝規(guī)格、 數(shù)量、品種不符,外觀毀損、短缺或缺陷,請在收到貨24小時內(nèi)申請退換貨;特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn),我們僅銷售188款生物醫(yī)學(xué)科研用品,款款都是爆款;因為少所以聚焦,聚焦甄選每一款產(chǎn)品,聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動通知
  • 品質(zhì)甄選,正品保證

  • 自營電商,廠家直采

  • 極簡主義,188精品