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Abnova/ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270/1kit/MAB14918
  • Abnova/ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270/1kit/MAB14918

Abnova/ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270/1kit/MAB14918

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貨號(hào): MAB14918
品牌: Abnova
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      • Specification
      • Gene Info
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human ACACA/ACACB.
      • Immunogen:
      • Synthetic phosphopeptide corresponding to residues surrounding S79 of human ACACA/ACACB.
      • Host:
      • Rabbit
      • Reactivity:
      • Human
      • Form:
      • Liquid
      • Purification:
      • Protein A purification
      • Isotype:
      • IgG
      • Recommend Usage:
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2000)Western Blotting (1:1000-1:5000)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
      • Storage Instruction:
      • Store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • Western Blot analysis of A431 cell lysate Lane 1: nontreated and Lane 2: treated with Lambda Protein Phosphatase with ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270 (Cat # MAB14918).
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with ACACA/ACACB (phospho S79) monoclonal antibody, clone RM270 (Cat # MAB14918).
      • Application Image
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • enlarge
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • enlarge
      • ACACA
      • ACACB
      • Gene Information
      • Entrez GeneID:
      • 31
      • Protein Accession#:
      • Q13085;O00763
      • Gene Name:
      • ACACA
      • Gene Alias:
      • ACAC,ACC,ACC1,ACCA
      • Gene Description:
      • acetyl-Coenzyme A carboxylase alpha
      • Omim ID:
      • 200350
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5" sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq
      • Other Designations:
      • ACC-alpha,OTTHUMP00000164069,acetyl-CoA carboxylase 1,acetyl-CoA carboxylase-alpha
      • Gene Information
      • Entrez GeneID:
      • 32
      • Protein Accession#:
      • Q13085;O00763
      • Gene Name:
      • ACACB
      • Gene Alias:
      • ACC2,ACCB,HACC275
      • Gene Description:
      • acetyl-Coenzyme A carboxylase beta
      • Omim ID:
      • 601557
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis.ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria.ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis.There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq
      • Other Designations:
      • acetyl-CoA carboxylase 2
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