Antibody reactive against mammalian transfected lysate.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
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Interspecies Antigen Sequence:
Mouse (78%); Rat (78%)
Datasheet:
Download
Applications
Western Blot (Transfected lysate)
Protocol Download
Application Image
Western Blot (Transfected lysate)
Gene Information
Entrez GeneID:
40
GeneBank Accession#:
NM_001094.4
Protein Accession#:
NP_001085.2
Gene Name:
ACCN1
Gene Alias:
ACCN,ASIC2,ASIC2a,BNC1,BNaC1,MDEG,hBNaC1
Gene Description:
amiloride-sensitive cation channel 1, neuronal
Omim ID:
601784
Gene Ontology:
Hyperlink
Gene Summary:
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq