UniProtSummary | FUNCTION:SwissProt:Mediatestheuptakeofglutamateintosynapticvesiclesatpresynapticnerveterminalsofexcitatoryneuralcells.Mayalsomediatethetransportofinorganicphosphate.
SIZE:560aminoacids;61665Da[MWofunprocessedprecursor]
SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane.Membrane;Multi-passmembraneprotein(Potential).Celljunction,synapse,synaptosome.
TISSUESPECIFICITY:Expressedinthecerebellum,cerberalcortexandhippocampus.Isoform2isexpressedspecificallyinretina.
SIMILARITY:Belongstothemajorfacilitatorsuperfamily.Sodium/anioncotransporterfamily.VGLUTsubfamily. |