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Abnova/CD45 monoclonal antibody PLUS (PE)/1kit/DH0090
  • Abnova/CD45 monoclonal antibody PLUS (PE)/1kit/DH0090

Abnova/CD45 monoclonal antibody PLUS (PE)/1kit/DH0090

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貨號: DH0090
品牌: Abnova
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      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • PE conjugated CD45 mouse monoclonal antibody.
      • Immunogen:
      • Human recombinant CD45
      • Host:
      • Mouse
      • Reactivity:
      • Human
      • Form:
      • Liquid
      • Conjugation:
      • PE
      • Concentration:
      • 0.03 mg/mL
      • Isotype:
      • IgG1, kappa
      • Quality Control Testing:
      • ResultsSandwich ELISAQC Testing of DH0090Sandwich ELISA performed with CD45 recombinant protein and CD45 monoclonal antibody PLUS (PE).ImmunofluorescenceQC Testing of DH0090Immunofluorescence staining performed on PBMC using CD45 monoclonal antibody PLUS (PE) (1:200).
      • Recommend Usage:
      • Immunofluorescence (1:200)LiquidCell™ SuperSlide™ (1.25 uL per slide)
      • Storage Buffer:
      • In 1x PBS, pH 7.4
      • Storage Instruction:
      • Store at 2-8°C. Do not freeze.
      • Protocol:
      • PDF DownloadProtocol Download
      • Amenable Platform:
      • LiquidCell™ negative enrichment cell isolation
      • Available Test:
      • 16 assays
      • Regulatory Status:
      • GMP grade
      • Instrument Compatibility:
      • Ventana™ BenchMark Stainer
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Immunofluorescence
      • Immunofluorescence
      • Immunofluorescence staining performed on CTCs from the patient recoverd by SuperSlide™. CD45 was detected via orange signal (PE).
      • Application Image
      • Immunofluorescence
      • Immunofluorescence
      • enlarge
      • Gene Information
      • Entrez GeneID:
      • 5788
      • Gene Name:
      • PTPRC
      • Gene Alias:
      • B220,CD45,CD45R,GP180,LCA,LY5,T200
      • Gene Description:
      • protein tyrosine phosphatase, receptor type, C
      • Omim ID:
      • 126200, 151460, 609532
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
      • Other Designations:
      • CD45 antigen,T200 glycoprotein,T200 leukocyte common antigen,glycoprotein,leukocyte-common antigen,protein tyrosine phosphatase, receptor type, c polypeptide
      • Gene Pathway
      • Cell adhesion molecules (CAMs)
      • Fc gamma R-mediated phagocytosis
      • Primary immunodeficiency
      • T cell receptor signaling pathway
      • Related Disease
      • Arthritis, Juvenile Rheumatoid
      • Arthritis, Rheumatoid
      • Ascariasis
      • Autoimmune Diseases
      • Cardiomyopathy, Dilated
      • Diabetes Mellitus, Type 1
      • Genetic Predisposition to Disease
      • Graves Disease
      • Hashimoto Disease
      • Hepatitis B
      • Hepatitis C
      • Hepatitis, Autoimmune
      • HIV Infections
      • Inflammatory Bowel Diseases
      • Lupus Erythematosus, Systemic
      • Lymphopenia
      • Multiple Sclerosis
      • Paraparesis, Tropical Spastic
      • Scleroderma, Systemic
          • ... see more
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