Immunogen | KLH-conjugatedlinearpeptidecorrespondingtotheC-terminusofhumanS100A4. |
Epitope | C-terminus |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | ThisantibodyrecognizesS100A4attheC-terminus. |
SpeciesReactivity | - Human
- Mouse
- Rat
- Bovine
- Canine
- Horse
|
SpeciesReactivityNote | DemonstratedtoreactwithHuman,Mouse,andRat. PredictedtoreactwithBovine,Canine,andEquinebasedon100%sequencehomology. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | TheproteinencodedbythisgeneisamemberoftheS100familyofproteinscontaining2EF-handcalcium-bindingmotifs.S100proteinsarelocalizedinthecytoplasmand/ornucleusofawiderangeofcells,andinvolvedintheregulationofanumberofcellularprocessessuchascellcycleprogressionanddifferentiation.S100genesincludeatleast13memberswhicharelocatedasaclusteronchromosome1q21.Thisproteinmayfunctioninmotility,invasion,andtubulinpolymerization.Chromosomalrearrangementsandalteredexpressionofthisgenehavebeenimplicatedintumormetastasis.Multiplealternativelysplicedvariants,encodingthesameprotein,havebeenidentified.[providedbyRefSeq,Jul2008]. |
GeneSymbol | |
PurificationMethod | AffinityPurfied |
UniProtNumber | |
UniProtSummary | SUBUNITSTRUCTURE:Homodimer.InteractswithPPFIBP1inacalcium-dependentmode.
TISSUESPECIFICITY:Ubiquitouslyexpressed.
SEQUENCESIMILARITIES:BelongstotheS-100family.
Contains2EF-handdomains. |
MolecularWeight | ~12kDaobserved |