The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
HDAC1 (Phospho-Ser421) Antibody
Synonyms
HD1; Histone deacetylase 1; RPD3L1
Immunogen
The antiserum was produced against synthesized peptide derived from human HDAC1 around the phosphorylation site of Ser421.
Immunogen Range
387-436
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:5000
Specificity
HDAC1 (Phospho-Ser421) Antibody detects endogenous levels of HDAC1 only when phosphorylated at Ser421.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
HDAC1
Database Links
Gene ID: 3065 Swiss-Prot #: Q13547
OMIM #: 601241 Unigene #: Hs.88556
Target Modification
Phospho
Modification Sites
H:S421 M:S421 R:S421
Application Images
Image 1
Western blot analysis of lysates from Jurkat cells treated with EGF 200ng/ml 30', using HDAC1 (Phospho-Ser421) Antibody. The lane on the right is blocked with the phospho peptide.