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  • avanti polar lipids/DSPE-PEG(2000) Azide/100mg/880228P-100mg

avanti polar lipids/DSPE-PEG(2000) Azide/100mg/880228P-100mg

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    • 880228 | DSPE-PEG(2000) Azide

      1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[azido(polyethylene glycol)-2000] (ammonium salt)

      DSPE-PEG(2000) Azide
      Info

      DSPE-PEG(2000) Azide

      1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[azido(polyethylene glycol)-2000] (ammonium salt)

      Cu-free click chemistry with readily synthesized biarylazacyclooctynones. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalyst.
      Also, refer to DSPE-PEG DBCO Avanti Number 880229

      Representative Structure

      The molecular weight and exact mass are averages based on the polydispersity of PEG.

      Data
      Hygroscopic
      Yes
      Light Sensitive
      No
      Molecular Formula

      C132H264N5O54P (average MW due to polydispersity of PEG)

      Percent Composition

      C 56.29%, H 9.45%, N 2.49%, O 30.67%, P 1.10%

      Purity
      >99%
      Stability
      1 Year
      Storage Temperature
      -20°C
      CAS Number
      1938081-40-3 CAS Registry Number is a Registered Trademark of the American Chemical Society
      FormulaWeight
      2816.519
      Exact Mass
      2814.78
      Synonyms
      1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethylene glycol)-2000] (ammonium salt)
      Downloads
      • ChemDraw File
      • 3D Structure
      • Structure
      • Safety Data Sheet
      • Safety Data Sheet
      References

      Xiao Y, Liu Q, Clulow AJ, Li T, Manohar M, Gilbert EP, de Campo L, Hawley A, Boyd BJ. PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery. Colloids Surf B Biointerfaces. 2019 Jul 15;182:110362. doi: 10.1016/j.colsurfb.2019.110362. [Epub ahead of print]

      PubMed ID: 31351271

      Girish A, Hickman DA, Banerjee A, Luc N, Ma Y, Miyazawa K, Sekhon UDS, Sun M, Huang S, Sen Gupta A. Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model. J Thromb Haemost. 2019 Jun 20. doi: 10.1111/jth.14552. [Epub ahead of print]

      PubMed ID: 31220416

      Paek J, Park SE, Lu Q, Park KT, Cho M, Oh JM, Kwon KW, Yi YS, Song JW, Edelstein HI, Ishibashi J, Yang W, Myerson JW, Kiseleva RY, Aprelev P, Hood ED, Stambolian D, Seale P, Muzykantov VR, Huh D. Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues. ACS Nano. 2019 Jun 18. doi: 10.1021/acsnano.9b00686. [Epub ahead of print]

      PubMed ID: 31194909

      Hood ED, Greineder CF, Shuvaeva T, Walsh L, Villa CH, Muzykantov VR. Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies. Bioconjug Chem. 2018 Sep 21. doi: 10.1021/acs.bioconjchem.8b00564. [Epub ahead of print]

      PubMed ID: 30240185

      Jewett, J.C., E.M. Sletten, and C.R. Bertozzi. (2010). Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc 132:3688-90.

      PubMed ID: 20187640
      Certificates of Analysis
      • Certificate of Analysis(Lot No. 880228C-10MG-A-012and 6307CIA012)
      • Certificate of Analysis(Lot No. 880228P-100MG-A-012and 6307PLA012)
      • Certificate of Analysis(Lot No. 880228P-10MG-A-012and 6307PIA012)
      • Certificate of Analysis(Lot No. 880228P-25MG-A-012and 6307PJA012)
      • Certificate of Analysis(Lot No. 880228P-500MG-A-012and 6307PPA012)
      • Certificate of Analysis(Lot No. 880228P-50MG-A-012and 6307PKA012)
      • Certificate of Analysis(Lot No. 880228P-50MG-A-013and 6307PKA01)
      • Certificate of Analysis(Lot No. 880228P-100MG-A-013and 6307PLA013)
      • Certificate of Analysis(Lot No. 880228P-25MG-A-013-6307PJA013and 6307PJA013)
      • Certificate of Analysis(Lot No. 880228P-50MG-B-013and 6307PKB013)
      • Certificate of Analysis(Lot No. 880228P-10MG-B-013and 6307PIB013)
      • Certificate of Analysis(Lot No. 880228P-10MG-C-013and 6307PIC013)
      • Certificate of Analysis(Lot No. 880228C-10MG-A-013and 6307CIA013)
      • Certificate of Analysis(Lot No. 880228P-100MG-B-013and 6307PLB013)
      • Certificate of Analysis(Lot No. 880228C-10MG-B-013and 6307CIB013)
      • Certificate of Analysis(Lot No. 880228P-50MG-C-013and 6307PKC013)
      • Certificate of Analysis(Lot No. 880228P-25MG-B-012and 6307PJB012)
      • Certificate of Analysis(Lot No. 880228P-100MG-B-012and 6307PLB012)
      • Certificate of Analysis(Lot No. 880228P-100MG-D-012and 6307PLD012)
      • Certificate of Analysis(Lot No. 880228P-25MG-B-013and 6307PJB013)
      • Certificate of Analysis(Lot No. 880228P-100MG-C-013and 6307PLC013)
      • Certificate of Analysis(Lot No. 880228P-50MG-D-013and 6307PKD013)
      • Certificate of Analysis(Lot No. 880228P-10MG-A-013and 6307PIA013)
      • Certificate of Analysis(Lot No. 880228P-25MG-C-013and 6307PJC013)
      • Certificate of Analysis(Lot No. 880228P-100MG-D-013and 6307PLD013)
      • Certificate of Analysis(Lot No. 880228P-50MG-E-013and 6307PKE013)
      • Certificate of Analysis(Lot No. 880228P-10MG-D-013and 6307PID013)
      • Certificate of Analysis(Lot No. 880228P-50MG-F-013and 6307PKF013)
      • Certificate of Analysis(Lot No. 880228P-50MG-G-013and 6307PKG013)
      • Certificate of Analysis(Lot No. 880228P-25MG-D-013and 6307PJD013)
      • Certificate of Analysis(Lot No. 880228P-100MG-E-013and 6307PLE013)
      • Certificate of Analysis(Lot No. 880228P-100MG-F-013and 6307PLF013)
      • Certificate of Analysis(Lot No. 880228P-10MG-F-013and 6307PIF013)
      • Certificate of Analysis(Lot No. 880228P-25MG-A-014and 6307PJA014)
      • Certificate of Analysis(Lot No. 880228P-50MG-A-014and 6307PKA014)
      • Certificate of Analysis(Lot No. 880228C-10MG-A-014and 6307CIA014)
      • Certificate of Analysis(Lot No. 880228P-100MG-A-014and 6307PLA014)
      • Certificate of Analysis(Lot No. 880228P-100MG-B-014and 6307PLB014)
      • Certificate of Analysis(Lot No. 880228P-50MG-B-014and 6307PKB014)
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