Polybead Acrylate Microspheres are monodisperse microspheres (2.5% solids in water) with surfaces that contain copolymers of styrene and an acrylic ester. The reactive ester sites on the polymer will furnish points for further organic reactions which may lead to innovative forms of activation (e.g. reaction with ammonia may lead to amide formation which may then undergo Beckmann rearrangement).