naphthoicacid,CD-271,DifferinProperties:
RelatedCategories | AnalyticalStandards,Analytical/Chromatography,Pharmacopeia&MetrologicalInstitutesStandards,USPStandards,USPStandardsA-B |
Description:
Generaldescription
ThisproductisprovidedasdeliveredandspecifiedbytheissuingPharmacopoeia.Allinformationprovidedinsupportofthisproduct,includingSDSandanyproductinformationleafletshavebeendevelopedandissuedundertheAuthorityoftheissuingPharmacopoeia.ForfurtherinformationandsupportpleasegotothewebsiteoftheissuingPharmacopoeia.
OtherNotes
Salesrestrictionsmayapply.
USPissuedSDScanbefoundhere.
Biochem/physiolActions
RetinoicacidanaloguethatisaRARβandRARγagoNIST(AC50valuesare2.2,9.3,22and>1000nMforRARβ,RARγ,RARαandRXRαreceptorsrespectively).Inhibitsproliferationandinducesapoptosisincolorectalcancercellsinvitro.Displayscomedolyticactivity.Itsuniquepharmacologicalpropertiesmakeitsuperiortootherretinoidsforthetreatmentofacne.
Safety:
RIDADR
NONHforallmodesoftransport