Tridodecylmethylammonium chloride (TDMAC) is a chloride ion-selective solvent polymeric membrane electrodes component. The ion-selective electrodes (ISEs; membrane electrodes) are electrochemical sensors useful in various analytical applications. TDMAC used as a polymer membrane-based electrode exhibits significant potentiometric response to heparin in the clinically relevant concentration range.
Additionally, TDMAC-heparin complexes are used as an antithrombogenic coating for catheters and tubing from which heparin is released slowly via an ion-exchange process. (See Polysciences catalog products 03813 and 03921 for TDMAC-heparin (Tridodecylmethylammonium heparinate) solutions).